The Metastatic Potential and Chemoresistance of Human Pancreatic Cancer Stem Cells
Cancer stem cells for human pancreatic ductal carcinoma (PDAC) have been identified, but neither the metastatic potential nor the chemoresistance of these cells has been adequately evaluated. The authors have addressed these issues by examining side-population cells isolated from the Panc-1 and BxPC3 lines of human PDAC cells, the oncogenotypes of which differ. [PLoS One] Full Article
Targeting Hypoxic Response for Cancer Therapy
The review provides an overview of the characteristics of the hypoxic tumor microenvironment, with particular focus on novel therapeutic strategies currently in clinical trials, targeting the adaptive response to hypoxia of cancer cells. [Oncotarget] Full Article
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INDUSTRY NEWS
Dream Team Gets $11.7 Million to Fight Brain Cancers
A “Dream Team” of top Canadian scientists, led by two outstanding figures in stem cell research, is launching a new attack on brain cancers. The team will receive $11.7 million over four years from Stand Up To Cancer Canada, Genome Canada, the Canadian Institutes of Health Research, the Cancer Stem Cell Consortium, and Ontario Institute for Cancer Research. [Canadian Stem Cell Foundation] Press Release
Propanc Discovers PRP Dramatically Suppresses Cancer Stem Cells
Propanc Health Group Corporation announced the company has filed a third patent regarding the use of its lead product, PRP, as a method to treat cancer by targeting cancer stem cell eradication, whilst sparing normal stem cells. [Propanc Health Group Corporation] Press Release
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