Targeting Histone Methyltransferase EZH2 as Cancer Treatment|
The author focuses on the recent advancements in EZH2 research, especially its dynamic regulation of epigenetic alterations in tumor cells, including the cancer stem cell population, and discusses perspectives and challenges for cancer treatment in the near future. [J Biochem] Abstract
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Altor BioScience and Shenzhen Beike Biotechnology Announce License Agreement for Immunotherapeutic ALT-803 in China|
Altor BioScience Corporation (Altor) and Shenzhen Beike Biotechnology Co., Ltd. announced that they have entered into a license agreement to develop and commercialize ALT-803, Altor’s proprietary interleukin-15 based superagonist complex, in China. ALT-803 is a potent immunotherapeutic agent capable of activating immune cell responses against hematologic and solid tumors and virally infected cells. [Altor BioScience Corporation (Business Wire)] Press Release
MabVax Therapeutics Enters Agreements with Memorial Sloan Kettering Cancer Center and Juno Therapeutics for Development of Anti-Cancer Therapeutics
MabVax Therapeutics Holdings, Inc. announced it has entered into agreements with Memorial Sloan Kettering Cancer Center and Juno Therapeutics for the development of novel therapeutic products using antibody targeting sequences derived from the fully-human antibodies discovered using the company’s internally developed antibody discovery platform. [MabVax Therapeutics Holdings, Inc.] Press Release
Clinical Trial to Test Safety of Drug Targeting Leukemia Cells
Researchers at the University of California, San Diego School of Medicine, in partnership with the California Institute for Regenerative Medicine and Celgene Corporation, a New Jersey-based biopharmaceutical company, have launched a Phase I human clinical trial to assess the safety and efficacy of a novel monoclonal antibody for patients with chronic lymphocytic leukemia. [University of California, San Diego School of Medicine (Medical Xpress)] Press Release
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